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Elevated linoleic acid intake becomes a risk factor for polycystic ovary syndrome by affecting ovarian granulosa cells
Researchers working with either compound should also consider downstream documentation requirements
It is also in the midst of early trials for LX9851, a non-incretin obesity drug that would be a potential alternative to GLP-1s
Additional safety unknowns include long-term effects on organ systems where HGF/c-Met signaling plays regulatory roles (liver, kidney, cardiovascular system), potential reproductive toxicity, and effects in individuals with pre-existing neoplastic conditions
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Compared to the docking conformation, the MD-stable conformation of GSH_a shows little change, suggesting that this binding mode may be reliable
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