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The lack of well-designed, comprehensive, human clinical studies means that there is little to no reliable scientific evidence to support the safety or effectiveness of BPC-157 in humans. A measure in the Defense authorization bill that passed the House would remove legally-available peptides from the DoDs prohibited substances list

Studies show that liraglutide 3.0 mg reduces gastric emptying by 23% at the 1-hour mark compared to placebo, while lower doses show a 13% decrease

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A., Alghamdi, A., Alkhashi, T., Alkhaldi, S

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Cardiovascular Outcomes# EXSCEL Trial (Exenatide)# The EXSCEL trial (Holman et al., NEJM 2017) enrolled 14,752 patients with type 2 diabetes (73.1% with prior cardiovascular disease) and followed them for a median of 3.2 years: Primary MACE endpoint : HR 0.91 (95% CI 0.83-1.00), p=0.06 for superiority Met non-inferiority but narrowly missed superiority (p=0.06) All-cause mortality was reduced by 14% (HR 0.86, p=0.016) in a secondary analysis EXSCEL confirmed cardiovascular safety but did not prove cardiovascular benefit -- a critical distinction