retatrutide triple agonist glp-1 gip glucagon phase 2 nejm 2023 peptide From Obesity to Metabolic Health:

Liao H, Wang X, Yang C et al (2025) Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions

Its not a household name yet

Melanin plays a crucial role in the browning of fruits, fungi, and vegetables, as well as in the pigmentation of mammalian skin

Current treatments (anticonvulsants, antidepressants, opioids) manage symptoms without addressing the underlying nerve damage

Studies in melanocyte cell lines and receptor-transfected systems have characterised the cAMP signalling response, tyrosinase induction, and melanin output associated with MT-1 receptor engagement

Weight gain in craniopharyngioma: a model for hypothalamic obesity