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Medicaid prescriptions for GLP-1s increased from about 1 million in 2019 to over 8 million in 2024, according to KFF
However, this meta-analysis included only one RCT 43 and one case-control study 51 for GLP-1RAs (but not the more recent semaglutide) 41
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These shifts may influence how GLP-1 medications feel and how well they work
While several GLP-1 medications exist, semaglutide (found in Ozempic and Wegovy ) and tirzepatide (found in Mounjaro and Zepbound ) have proven to be the most effective for weight loss
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