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The approval marked a pivotal moment in endocrinology, introducing a new mechanism of action that differed substantially from older insulin-based and sulfonylurea therapies
A study of patients with non-alcoholic fatty liver disease (NAFLD) revealed that giving 300 mg of glutathione daily for four months resulted in significant reductions in elevated ALT (an enzyme associated with liver damage), triglycerides, and ferritin
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Patients who failed to meet specific glycemic goals during the studies were treated with metformin rescue
This precision-wellness approach helps distinguish individual variation from true safety concerns, enabling confident, informed treatment decisions
Other evidence-based interventions include: Optimising management of associated conditions such as diabetes, hypertension, and dyslipidaemia Coffee consumption, which observational studies associate with reduced liver disease progression Avoiding hepatotoxic medications when possible Regular monitoring through your GP is essential
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