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Curr Top Med Chem 15:458483
In contrast, the gdh3 / gdh3 mutant showed a higher concentration of ATP, NAD + , and NADH, but not NADP + or NADPH, when incubated in proline medium when compared to the wild-type strain (Figs 7 and 8)
All of these functions decline during menopause
Collectively, these results indicate that TRIP12 conjugates K29-linked ubiquitin chains onto OTUD5, which is resistant to OTUD5 DUB activity
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