This study first reveals that ROS-driven HIF-1-BNIP3/NIX-mediated mitophagy mitigates hypoxia-induced inflammation and apoptosis, contributing to the enhanced hypoxia adaptation observed in Tibetans
(2015) study
1 Introduction While Roux-en-Y gastric bypass (RYGB) leads to substantial and sustained weight loss (WL) in the majority of individuals, along with significant improvements or even resolution of obesity-related conditions, especially type 2 diabetes (T2D) ( Although the mechanistic aspects of metabolic bariatric surgery (MBS), consisting in gastric volume restriction and intestinal malabsorption, were initially thought to be the only culprits for the observed response to MBS, it is long known that they are just part of the equation
Liraglutide lowers body weight set point in DIO rats and its relationship with hypothalamic microglia activation
Ward PP, Paz E, Conneely OM
Vacante F, Senesi P, Montesano A, Frigerio A, Luzi L, Terruzzi I (2018) L-carnitine: an antioxidant remedy for the survival of cardiomyocytes under hyperglycemic condition