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Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels

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41589_2021_915_MOESM10_ESM.mpeg Supplementary Video 8 Representative movie for 100 ns MD simulation of GPX4 U46C-K48A with the camera zoomed in for a close-up of the active site

Wenn nun aufgrund eines Selenmangels die Phase I der Entgiftung nicht richtig verlaufen kann, dann gert auch die Phase II ins Stocken, in der Gifte in eine wasserlsliche Form gebracht werden, damit sie ber die Nieren ausgeschieden werden knnen