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Description

Activation of the -opioid receptor signaling pathway likely influences the reward circuitry through vagal afferent connections that influence the central opioid signaling pathways

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Furthermore, surviving HSAAR males in two founding lines (L78 and L141, corresponding to transgene copy number, and AR mRNA and protein expression) revealed a relationship between greater AR expression and severity of disturbance in body mass, motor function, EDL muscle size, and EDL myofiber number at 10 to 75 weeks of age

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