62 GLP-1 receptor activation inhibits glucagon secretion, whereas GIP receptor activation increases glucagon secretion during normoglycemia or hypoglycemia, but suppresses glucagon secretion under hyperglycemic conditions
Decorin increases 302% at 1 nanomolar concentration, and this small proteoglycan regulates collagen synthesis and organization, essentially serving as an architect for proper structural protein arrangement
Haines M, et al
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Moving toward a systems-level understanding, empowered by interactomics, CRISPR technologies, AI-driven modeling and precision biomarker science, will profoundly transform how we interpret disease biology and develop therapeutics
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