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Studies utilizing mouse models of T2DM-associated cognitive dysfunction and high glucose-stimulated PC12 cell models have established a link between DACD pathogenesis and ferroptosis mediated by GPX4 suppression
It help in the metabolism of long-chain fatty acids, the clearance of lactic acid, and the detoxification of ammonia
N Engl J Med 377(1):1327 Wilding JPH et al (2021) Once-weekly semaglutide in adults with overweight or obesity
"This is a major step forward for patients with obstructive sleep apnea." "Today, many cases of OSA go undiagnosed and untreated, leaving millions at risk for serious health consequences," added Patrik Jonsson, president of Lilly Cardiometabolic Health and Lilly USA
All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas
Nature Genet
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