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The fundamental mechanism is the activation of phase II detoxification enzymes or antioxidase controlled by Nrf2/ARE, including the expression of NAD(P)H quinone dehydrogenase 1 (NQO1), GPX, and superoxide dismutase (SOD) (Truong et al., 2014)

The percentage of 5-mC detected in DNA samples using a 5-mC DNA ELISA Kit strongly correlates with mass spectrometry (MS) data demonstrating 5-mC found in the same gDNA sample

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Common Variants in MTHFR MTHFR There are a few common MTHFR gene variants that can decrease the activity of the enzyme

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and Phase III transporters export conjugates for excretion