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doi: 10.1084/jem.20210518 20 ChenG

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A majority of the trial participants had a body mass index above 30

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C1q/TNF-related protein 5 upregulates 12/15-LOX through STAT6 signaling to accelerate the development of atherosclerosis, while inhibition of 12/15-LOX reduces LDL oxidation and improves atherosclerosis

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