Mechanism: Binds to the Ghrelin receptor (GHS-R1a)
Reported benefits (per available research): Studied in animal (rodent) models for tendon, ligament, and muscle healing, with researchers attributing effects to promotion of angiogenesis and fibroblast activity (preclinical studies from a Croatian research group at the University of Zagreb, spanning several decades) Originally investigated for gastroprotective properties
doi:10.4103/1673-5374.320969 Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, Mu N, Gu J, Zhang W, Wang Y, Zhang Y, Zhang W
Supports a Healthy Inflammatory Response : Promotes a balanced inflammatory response through your body's natural pathways, contributing to overall vitality and wellness
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Therefore, exploring the role of perioperative gut microbiota and elucidating the gut-brain axis will enhance our understanding of the relationship between gut microbiota and PND