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To view digital features for this article go to Introduction Semaglutide is a glucagon-like peptide-1 (GLP-1) analogue that is the first and, thus far, only GLP-1 receptor agonist (GLP-1RA) to be formulated as a once-daily oral tablet for people with type 2 diabetes (T2D) [1,2,3,4]

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A separate study from Mass General Brigham found that women who discontinued GLP-1 medications before or early in pregnancy gained an average of 7.2 pounds more during pregnancy and experienced higher rates of gestational diabetes, hypertensive disorders, and preterm birth

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