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In a study by Zhang et al., activation of GLP-1R was shown to mitigate novel-object recognition memory dysfunction in neuropathic pain model mice by modulating the hippocampal AMPK/NF-B signaling pathway [69] (Fig
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Laperche S, Lunel F, Izopet J, Alain S, Deny P, Duverlie G, Gaudy C, Pawlotsky JM, Plantier JC, Pozzetto B, Thibault V, Tosetti F, Lefrere JJ: Comparison of Hepatitis C Virus NS5b and 5' Noncoding Gene Sequencing Methods in a Multicenter Study
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Long-acting formulations currently hold the largest GLP-1 Drug Market share at 57% due to their prolonged effects and ability to minimize patient dosing frequency
