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An improved Graves disease model established by using in vivo electroporation exhibited long-term immunity to hyperthyroidism in BALB/c mice
This setting may allow earlier insights into treatment effects, particularly via DNA-methylation based epigenetic clocks and other emerging aging biomarkers, which are recently being considered as outcome measures in double-blind, randomized geroscience trials 17 and global competitions testing gerotherapeutics 18
Biochim Biophys Acta 1648(12):210218 Simic T, Dragicevic D, Savic-Radojevic A, Cimbaljevic S, Tulic C, Mimic-Oka J (2007) Serum gamma glutamyl-transferase is a sensitive but unspecific marker of metastatic renal cell carcinoma
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