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In mouse models, the team introduced combined therapy including PD-L1 blocker and cyst(e) inase (a bioengineered enzyme that degrades cystine and cysteine) and such treatment can enhance the efficacy of CTL-mediated anticancer effects, supporting the idea that inducing ferroptosis could be considered a productive way for treating cancer and overcoming immunotherapy resistance (Wang et al., 2019)
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Furthermore, to further ensure sterility, the vials of this Pfizer bacteriostatic water for injection, USP are constructed using a plastic-based flip-flop self-healing lid that closes as soon as the needle is retracted after taking a dose
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