retatrutide phase 2 trial duration weight loss What the clinical trials say about RETA dosing & (phase data) (clarification for those asking) : r/ Retatrutide Lilly's triple agonist, retatrutide, delivered – retatrutide side effects phase 2

doi: 10.1016/j.celrep.2019.10.070 167 TalukdarSOhDYBandyopadhyayGLiDXuJMcNelisJet al

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They also act on the brain. The direct effect of GLP-1s on the brain can partially explain their emotional impact

[12] GH release stimulates protein synthesis and nitrogen retention, which is the rationale for investigating GH secretagogues in catabolic states such as post-surgical recovery, critical illness, prolonged bedrest, and age-related muscle wasting (sarcopenia)

The authors observed a 50% increase in MDA, a reduction in SOD, GPx4, and Xc- protein expression, and a 60% increase in ACSL4 levels