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A few reviewers mention mild digestive changes during the first week or two, which is expected with any prebiotic supplement as the gut adjusts to increased fiber and bacterial shifts

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Direct vascular effects [edit] Acetylcholine in the serum exerts a direct effect on vascular tone by binding to muscarinic receptors present on vascular endothelium

However, close monitoring is necessary

Collectively, astrocytic state transitions and the resulting heterogeneity enables glial networks to flexibly sustain neuronal activity and preserve circuit homeostasis

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