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Intracerebroventricular administration of PF-5190457 attenuates ghrelin-induced food intake in male mice only, but reduces HFD-induced binge-eating behaviour in both sexes [242]
Welle S, Campbell RG
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3 Metformin acts on mitochondria to regulate oxidative stress One of the mechanisms of action of metformin against glioma is to affect the production of ATP and regulate cellular oxygen consumption ( de novo lipogenesis
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