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Rapid improvement in blood sugar control can temporarily worsen diabetic retinopathy, so regular eye check-ups are important
Earlier concerns regarding acute pancreatitis and pancreatic cancer have largely been alleviated by long-term randomized trials that have not confirmed a causal association, although reporting biases and diagnostic complexity remain considerations, and continued pharmacovigilance is recommended
GA was selected for in-depth investigation: as a trihydroxybenzoic acid abundant in gallnuts, tea, and various fruits, it is a well-documented potent antioxidant, anti-inflammatory, and chemopreventive agent 24
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Next step: After 4 weeks at 50 units, assess progress
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