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Scenario 3: Running 12 continuous weeks with no rest period

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doi: 10.1016/j.intimp.2025.114562 32 XueMYangFLeYYangYWangBJiaYet al

These developments are consistent with the evolving understanding of the gastrointestinal tract as a key endocrine organ that regulates appetite, glucose homeostasis, energy expenditure, and gastrointestinal motility through a complex network of hormonal signals [20]