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The expression of the endogenous mTORC1 inhibitor sestrin 2 is induced by UVB and balanced with the expression level of sestrin 1

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doi: 10.3390/ijms22157765

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For latest data, check ClinicalTrials.gov (NCT# for CagriSema: NCT04982562) or Novo Nordisk pipeline

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Journal of Cosmetic Dermatology 14(2):83-90. [doi.org]

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According to studies, it can enhance sleep efficiency, restore circadian rhythms, and improve the quality of sleep without sedation or drowsiness the following day

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Patient selection criteria are not well-established, and determining which patients are most likely to benefit from these therapies requires clinical judgment based on limited evidence

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