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Standard cagrilintide dosing follows a 12-week titration from 0.6mg to 2.4mg weekly (0.6mg weeks 1-4, 1.2mg weeks 5-8, 1.8mg weeks 9-12, 2.4mg week 13+)

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Endurance training prevents inflammation and apoptosis in hypothalamic neurons of obese mice

SURMOUNT-1 enrolled 2,539 adults with obesity or overweight without type 2 diabetes and tracked them over 72 weeks