[125] Storage and excretion [edit] How fast B 12 levels change depends on the balance between how much B 12 is obtained from the diet, how much is secreted and how much is absorbed
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Other groups who may benefit include: Patients following gastric surgery (gastrectomy, bariatric procedures) where intrinsic factor production or absorption sites are compromised Individuals with malabsorption disorders such as Crohn's disease, coeliac disease, or chronic pancreatitis Strict vegans and vegetarians with dietary insufficiency, though oral supplementation is usually tried first Elderly patients with atrophic gastritis or reduced gastric acid production Patients on long-term metformin or proton pump inhibitors, which can impair B12 absorption [6] [8] Individuals with nitrous oxide exposure (recreational or medical), which can cause functional B12 deficiency Diagnosis typically involves serum B12 measurement, with levels below approximately 148 pmol/L (though thresholds vary between laboratories) generally indicating deficiency
Youll want to avoid areas with bones and large visible blood vessels, like the back of your hand
Each 10 mL multi-dose vial contains 100 mcg/mL of Vitamin B12, equivalent to ten 1 mL weekly injections, making it a convenient and cost-effective option for patients requiring regular supplementation
Are B12 injections safe