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Medications like Ozempic and Mounjaro were originally developed and FDA approved to treat people with Type 2 diabetes

Its important to keep in mind that these numbers reflect averages from clinical trials where patients also received diet and lifestyle support

Furthermore, these authors reported a strong link between oxidative stress, inflammation, uremic toxins, and eryptosis [260]

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In addition, significant transcriptional induction of several PR genes as well as differential changes in multiple GST transcripts were observed (Sana et al., 2010)

In contrast, chronic administration of GIP to obese mice [155], or short term GIP infusion within WAT of humans [156], augments adipose tissue inflammation, characterised by increased infiltration of mononuclear cells and enhanced cytokine expression