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These Phase II conjugation reactions result in the formation of larger and more polar molecules that are generally less biologically active and more readily excreted from the body
5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the cytosolic enzyme that methylates nicotinamide to 1-methylnicotinamide (1-MNA) using S-adenosyl-L-methionine (SAM) as the methyl donor
S2CID 5916660
Research published by Song et al
It plays a key role in: Enhancing the production of white blood cells, which fight infections
Cell 80 , 592606.e598 (2020)
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