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T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

Intriguingly, PD-L1, a key immunoregulatory molecule, can act as an RNA-binding protein to stabilize transcripts encoding DDR proteins such as BRCA1, MRE11, and RAD50, thereby enhancing DNA repair and promoting resistance to radiotherapy and chemotherapy

Once absorbed into the bloodstream, NAC is quickly hydrolyzed into active cysteine, which then pairs with circulating glycine to actively synthesize glutathione inside the cells

The coculture with endometrial stromal cells induced depressed cytotoxicity and aberrant metabolism of CD8+ T cells via signal transducer and activator of transcription (STAT)1/programmed cell death (PDCD)1 pathway

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