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10.1002/advs.202204365 80 YinS.-Y.SongG.YangY.ZhaoY.WangP.ZhuL.-M.et al (2019)
But not everyone will have access to the drugs at an affordable price
Specific Populations No clinically significant differences in semaglutide pharmacokinetics were observed based on age (18 years old), sex, race (White, Asian or Black or African American), ethnicity, body weight (40 to 188 kg), upper GI disease (i.e., chronic gastritis and/or gastroesophageal reflux disease), hepatic impairment (i.e., mild, moderate, severe based on the Child-Pugh system) and renal impairment (i.e., mild, moderate, severe, end staged renal disease)
Cycling intake helps reduce risks and prevent plateauing of effects
GLP-1s as a class took off when semaglutide was approved for chronic weight management in 2021
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