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In a mouse model of shoulder arthrofibrosis, multiple intraarticular injections of human relaxin-2 restored range of motion and eliminated capsular fibrosis

This results in increased levels of H 2 O 2 in the peroxisome, which can then damage mitochondria, particularly if they have insufficient antioxidant defenses, such as depleted glutathione levels (Walton and Pizzitelli, 2012)

In contrast, only a weak association was found between oxidative stress and herpes infection in captive animals

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