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In vivo and in vitro models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expression of genes related to glutathione anabolic metabolism (GCLC, GCLM, and SLC7A11) was significantly down-regulated
Biochem.Pharmacol 10-20-1992;44(8):1637-1649
Because the aqueous solution presents a beautiful blue color, it is also known as blue copper peptide (GHK-Cu)
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