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Sleep Medicine, 72 , 28-36
The label says "any time of day, with or without meals" for injectable formulations
R.TavoraB.DAmicoG.et al (2012)
An appropriate dose is crucial to prevent muscle and joint discomfort
Signs of overmedication include: Heart palpitations or rapid heart rate Anxiety or nervousness (beyond what would be expected from the weight loss transition) Tremor Heat intolerance Insomnia Excessive weight loss beyond expected A falling TSH below target range confirms the need for dose reduction
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