This fundamental misunderstanding leads more to the suppression of symptoms than addressing the true cause and ultimately to healing
In five patients who did not receive dexamethasone treatment, a severe phenotype accompanied by tendon tear or rupture was observed, and the total incidence proportion declined from 0.75% to 0.43% with dexamethasone (Supplementary Table S5)
Among these regulators, small regulatory peptides, often described under an umbrella term matrikines, attract particular interest [ 15 ]
From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles
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Multidisciplinary evaluation Our programs typically begin with medical record review and coordinated diagnostics to identify likely drivers and rule out red flags