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However, it is important to recognise that whilst they are widely available, the regulatory framework for food supplements differs significantly from that of licensed medicines, and claims made about their efficacy should be evaluated critically against available evidence
Accessed December 2, 2025
In a maintenance trial, nausea affected 47% of participants during escalation but fell to 14% after the same 2.4 mg dose was held. Receptor exposure stayed constant
Flushing occurs in about 21% and headache in 12%
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