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Step 6: Insert the Needle at the Correct Angle For a half-inch needle, insert at 45 degrees to the skin surface when using the pinch technique or when injecting at a lean site

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signs of an allergy may include rash, hives, itching, or even anaphylaxis (a severe allergic response) in highly sensitive individuals

The aggregates are visible as cloudiness or, in severe cases, as white flakes