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and Melanotan II, which has been used to increase tanning abilities

In trials focused on people with type 2 diabetes, a population already at elevated heart risk, GLP-1s consistently reduced serious cardiovascular events by 1226% depending on the drug and population, with strong results for stroke prevention

Tirzepatide is the better-evidenced molecule for perimenopausal women, with about 23% body weight loss versus 3% on placebo in a SURMOUNT-1 post-hoc analysis

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What the Research Says Although research directly linking GLP-1 therapy to reduced back pain is still emerging, early evidence is promising