In the withdrawal cohort, regaining half of the lost weight raised insulin resistance by roughly 35% to 40%, and blood pressure rose as weight returned. Taper frameworks combine at least 1.2 g/kg of protein with resistance training before the drug signal fades
And the two medications differ meaningfully here
Progress in Molecular Biology and Translational Science
Some weight regain is possible if you haven't established sustainable lifestyle habits
MD: Writing review & editing, Formal analysis
PLoS One 12(4):e0175796 Karmi O, Marjault HB, Pesce L, Carloni P, Onuchic JN, Jennings PA, Mittler R, Nechushtai R (2018) The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease