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Following the discovery of exendin-4, pharmaceutical companies recognised the therapeutic potential and began developing synthetic versions of this peptide for human use

1 Across participants, predicted weight loss ranged from 6% to 20% of starting body weight, and the estimated chance of experiencing nausea ranged from 5% to 78%, depending on genetic and clinical factors

Efficacy and safety of dulaglutide versus sitagliptin after 52 weeks in type 2 diabetes in a randomized controlled trial (AWARD-5)

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