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These meds have historically run upward of $1,000 without insurance (and coverage is still limited)though both Eli Lilly (Zepbound) and Novo Nordisk (Wegovy) have recently cut that price in half, to $499 a month, for folks without coverage who opt in to direct-pay programs with the drugmakers

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Tirzepatide (Mounjaro for diabetes, Zepbound for weight management) is a dual GIP/GLP-1 receptor agonist with similar effects