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14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below
The post says appetite suppression can reduce fluid intake, while glucose excreted in the urine raises urinary glucose concentration, and that the combination may create an environment favorable to bacterial growth
A GLP-1s effectiveness will greatly depend on how well formulated it is
In my experience, it also requires sustained effort from the patient to corral a doctors office into submitting the necessary paperwork
But our scientists were undaunted
Critical Care Medicine
