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doi: 10.1016/j.jep.2015.01.026 4 AjithT

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Arch Dermatol 123(3):363368 Hassan Saad R, Halawa SM, Zidan AM, Emara NM, Abdelghany OA (2020) Malignant transformation of oral squamous cell papilloma: a case report

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Bleeding-related events as adjacent gynaecological signals Although bleeding is not a vaginal mucosal endpoint, it is clinically adjacent because patients may describe spotting as vaginal bleeding and present alongside discharge/pain

For example, bowel obstruction (a blockage in your intestines) Severe or long-lasting constipation can cause complications