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Prior to treatment, clients are evaluated to ensure safety and appropriate IV selection

The MetroHealth System, Cleveland OH, IRB determined research using TriNetX as described in this study was not Human Subject Research, and IRB approval is not required (more details in the Supplementary Appendix)

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doi: 10.1016/j.bbrc.2019.06.015 96 WeiC

Investigators must show that engineered cargo reaches the intended recipient cells at a biologically effective dose without disrupting normal metabolism in other organs

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