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Some fertility and PCOS protocols use 4,000mg of myo-inositol daily, often divided into two doses.21 Reaching that level with Ritual would require doubling the serving size, which would also increase NAC from 600mg to 1,200mg and CoQ10 from 100mg to 200mg

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by Dr Hayley Willacy, FRCGP Further reading and references Vitamin B12 deficiency in over 16s: diagnosis and management NICE guidance (March 2024) PHE

Progressive cartilage degradation indicates the chondrocyte imbalance, which ultimately favors the catabolic processes