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If constipation is already severe at 1.0 mg, escalating to 2.4 mg is likely to make it intolerable
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Melanotan II (sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH) is a synthetic cyclic analogue of -MSH (-melanocyte-stimulating hormone) developed at the University of Arizona in the 1980s
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