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Diarrhea, vomiting, and decreased appetite round out the common GI effects

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University of Rochester

Commercial tirzepatide products like Mounjaro and Zepbound contain carefully balanced excipients and buffers that help maintain stability, but these additives only work within specified storage conditions

Researchers also found that the decrease in lean muscle mass was not all from skeletal muscles, but from other body tissues, including the liver

In some studies, correction of neurological signs or clinical manifestations has also been sought