You should consider reaching out (virtually or in person) if you have: Not had a bowel movement for more than 3 to 4 days Severe abdominal pain or distention Blood in your stool Constipation that significantly impacts quality of life Constipation that doesn't improve with your usual self-management strategies How pelvic floor physical therapy can help Pelvic floor physical therapy can be a very helpful tool when managing GLP-1-related constipation
doi:10.1001/jama.2023.24945 Link: Domecq JP, Prutsky G, Mullan RJ, et al
Accordingly, moderate lean tissue decline observed during GLP-1RA-induced weight loss could be interpreted as a physiological component of body composition change rather than evidence of pathological sarcopenia, unless accompanied by functional deterioration
Yang Y, Li H, Liu K, Zou L, Xiang S, Geng Y, et al
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What happens when you stop tirzepatide Understanding discontinuation outcomes helps you set realistic expectations and plan for long-term success, whether you intend to use tirzepatide indefinitely or as a time-limited intervention