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Discontinuation rate: The 11.3% discontinuation due to adverse events at the 12mg dose is higher than seen with Mounjaro (approximately 7%) at its highest dose
Additionally, metabolic changes that lead to microenvironment alterations, such as the deprivation of oxygen and nutrients, may regulate GPER expression by feedback, creating a complex regulatory network
They should focus on a balanced diet, regular exercise, and being mindful of alcohol consumption
Zhang, L., Ye, B., Chen, Z
Jama 322 (13), 1313
In a multivariate model, the GLP-1-RA group was associated with 50% responder-rate at M6 (Fig
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![PDF] Tirzepatide-Induced Injection Site Reaction](https://figures.semanticscholar.org/18fb0b8dbc04c04a7b5177d9fd87256fc7c060bb/2-Figure1-1.png)
