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Some research indicates that lithium may enhance the activity of glutamate-cysteine ligase, a rate-limiting enzyme in glutathione synthesis, but the exact molecular interactions remain unclear
The GT superfamily has two binding sites, a G-site for glutathione, and H-site for the hydrophobic electrophile of the other substrate
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These should only be performed by a trained professional
We also created plasmid constructs to express recombinant glutathione reductase and 25-hydroxylase
J Clin Endocrinol Metab, 96(1), 150158
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