140,141 This synergistic impact on both the metabolic and genetic aspects of aging makes GLP-1 RAs a distinctive approach to postpone cellular aging and encourage longevity
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In addition, our analysis findings revealed high persistence rates in the use of SGLT2is [medication possession ratio (MPR): 93.1%] and GLP-1RAs (MPR: 88.8%) among our study patients, thereby minimizing the potential of misclassification bias caused by the intention-to-treat scenario in a study with a long-term observational period
However, branded products may face higher costs, potentially impacting patient affordability, and insurance coverage varies, which could affect practice revenue (Compound versions halted by FDA)